63 Diseases That Start With The Letter N

Have you ever wondered about diseases that start with the letter “N”? Wonder no more, this article is exactly what you are looking for.

In this article, I will dive into the realm of some known and lesser-known diseases beginning with this enigmatic letter N, aiming to raise awareness and understanding.

So, without any further ado, let’s embark on this fascinating journey and broaden our understanding of diseases that start with the letter N.


Diseases That Start With N

The followings are some known and lesser-known diseases that begin with the letter N (In alphabetical order):

1. Nail Fungus: Nail fungus, also known as onychomycosis, is a common fungal infection that affects the nails. It can lead to discoloration, thickening, and crumbling of the nails. Keeping nails clean and dry and using antifungal treatments are essential for managing nail fungus.

2. Nail Trauma: Nail trauma refers to injuries or damage to the nails caused by accidents or repetitive actions. It can lead to pain, bleeding, or deformities of the nails. Treatment involves proper wound care and, in severe cases, medical intervention to address any underlying fractures or complications.

3. Narcolepsy: Narcolepsy is a chronic neurological disorder characterized by excessive daytime sleepiness and sudden, uncontrollable sleep attacks. It can significantly impact daily life and lead to accidents if left untreated. Management may involve medications and lifestyle adjustments to improve sleep quality.

4. Nasal and Sinus Cancer: Nasal and sinus cancer is a rare type of cancer that develops in the nasal cavity or the sinuses. It may cause symptoms such as persistent nasal congestion, nosebleeds, and facial pain. Treatment options include surgery, radiation therapy, and chemotherapy.

5. Nasal Polyps: Nasal polyps are noncancerous growths that can develop in the nasal passages or sinuses. They can cause nasal congestion, difficulty breathing, and loss of smell. Medications and, in some cases, surgical removal are used to manage nasal polyps.

6. Nasopharyngeal Cancer: Nasopharyngeal cancer is a type of head and neck cancer that originates in the nasopharynx, the upper part of the throat behind the nose. Symptoms may include neck lumps, nasal congestion, and hearing loss. Treatment involves radiation therapy, chemotherapy, and surgery.

7. Nausea: Nausea is a sensation of discomfort in the stomach that often precedes vomiting. It can be caused by various factors, including infections, motion sickness, and pregnancy. Addressing the underlying cause and using antiemetic medications can help alleviate nausea.

8. Nearsightedness (Myopia): Nearsightedness, or myopia, is a common refractive error where distant objects appear blurry, but close-up objects are clear. It is usually corrected with eyeglasses, contact lenses, or refractive surgery.

9. Neck Pain: Neck pain can result from muscle strain, poor posture, or underlying medical conditions such as arthritis or herniated discs. Rest, physical therapy, and pain relievers are commonly used to manage neck pain.

10. Necrotizing Enterocolitis: Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease that primarily affects premature infants. It involves inflammation and damage to the intestines and requires immediate medical intervention, including antibiotics and possible surgery.

11. Necrotizing Fasciitis: Necrotizing fasciitis, often referred to as “flesh-eating bacteria,” is a rare but severe bacterial infection that rapidly destroys the body’s soft tissues. It requires aggressive medical treatment, including surgery and intravenous antibiotics.

12. Neisseria Meningitidis Infection: Neisseria meningitidis is a bacterium that can cause meningococcal disease, including meningitis and septicemia. It is a medical emergency and requires urgent treatment with antibiotics.

13. Neonatal Jaundice: Neonatal jaundice is a common condition in newborns, characterized by yellowing of the skin and eyes due to high bilirubin levels. In most cases, it resolves on its own, but severe cases may require phototherapy or other treatments.

14. Neonatal Lupus: Neonatal lupus is a rare autoimmune condition that can affect infants born to mothers with certain autoimmune antibodies. It can cause skin rashes and, in some cases, affect the heart. Treatment focuses on managing symptoms and may not be necessary in all cases.

15. Neonatal Respiratory Distress Syndrome (NRDS): Neonatal respiratory distress syndrome is a breathing disorder that primarily affects premature infants due to underdeveloped lungs. Treatment involves respiratory support and surfactant therapy to improve lung function.

16. Nephritis: Nephritis is inflammation of the kidneys, which can affect kidney function and lead to various symptoms, including blood in the urine and swelling. The underlying cause determines the treatment approach, which may include medications and lifestyle changes.

17. Nephroblastoma (Wilms Tumor): Nephroblastoma, also known as Wilms tumor, is a type of kidney cancer that primarily affects children. Early detection and a combination of surgery, chemotherapy, and radiation therapy offer good chances of cure.

18. Nephrocalcinosis: Nephrocalcinosis is the accumulation of calcium deposits in the kidneys, which can lead to kidney stones and impaired kidney function. Treatment focuses on managing the underlying cause and preventing complications.

19. Nephrogenic Diabetes Insipidus: Nephrogenic diabetes insipidus is a condition where the kidneys cannot concentrate urine properly, leading to excessive thirst and frequent urination. Treatment involves managing fluid intake and using medications to improve kidney response to antidiuretic hormones.

20. Nephrogenic Systemic Fibrosis: Nephrogenic systemic fibrosis is a rare and serious condition that affects individuals with severe kidney disease. It leads to skin thickening and joint stiffness. Preventing the use of certain imaging agents in susceptible individuals is crucial to avoid this condition.

21. Nephropathia Epidemica: Nephropathia epidemica is a form of hemorrhagic fever caused by hantavirus infection. It can lead to kidney failure and other severe symptoms. Preventive measures include avoiding contact with rodents and their droppings.

22. Nephropathy: Nephropathy refers to damage or disease of the kidneys, often caused by conditions like diabetes or hypertension. Managing underlying health conditions and adopting a kidney-friendly lifestyle are vital for slowing the progression of nephropathy.

23. Nephrotic Syndrome: Nephrotic syndrome is a kidney disorder characterized by proteinuria (excess protein in urine), edema, and low protein levels in the blood. It can result from various underlying conditions and requires medical management, including medications and dietary changes.

24. Neuralgia: Neuralgia is a type of chronic pain caused by nerve irritation or damage. It can affect various parts of the body, and treatment may include medications to alleviate nerve pain.

25. Neuroblastoma: Neuroblastoma is a type of cancer that develops from immature nerve cells, primarily affecting infants and young children. Treatment involves a combination of surgery, chemotherapy, radiation therapy, and immunotherapy.

26. Neurocardiogenic Syncope: Neurocardiogenic syncope, also known as vasovagal syncope, is a common form of fainting caused by a sudden drop in heart rate and blood pressure. It can be triggered by various factors such as emotional stress or standing for prolonged periods. Management involves identifying triggers and making lifestyle adjustments to prevent episodes.

27. Neurocysticercosis: Neurocysticercosis is a parasitic infection of the brain caused by ingesting tapeworm eggs. It can lead to neurological symptoms such as seizures and headaches. Antiparasitic medications and anti-inflammatory drugs are used to treat neurocysticercosis.

28. Neuroendocrine Tumors: Neuroendocrine tumors (NETs) are rare tumors that arise from hormone-producing cells in various organs. Treatment depends on the tumor type, location, and stage and may involve surgery, targeted therapy, or somatostatin analogs.

29. Neurofibroma: Neurofibromas are noncancerous tumors that grow on nerves, often affecting the skin and peripheral nerves. In some cases, they may cause pain or other symptoms that require medical intervention.

30. Neurofibromatosis: Neurofibromatosis is a genetic disorder that causes tumors to form on nerves throughout the body. There are two types: NF1 and NF2, each with distinct symptoms and complications. Regular monitoring and management of associated health issues are crucial for individuals with neurofibromatosis.

31. Neurogenic Bladder: Neurogenic bladder is a condition where nerve damage disrupts the normal bladder function, leading to problems with urinary control. Treatment options include medications, catheterization, and bladder training.

32. Neuroleptic Malignant Syndrome (NMS): Neuroleptic malignant syndrome is a rare but potentially life-threatening reaction to certain medications used to treat psychiatric disorders. It can cause high fever, muscle stiffness, and altered mental status. Immediate medical attention and discontinuation of the offending medication are necessary.

33. Neuromyelitis Optica: Neuromyelitis optica, also known as Devic’s disease, is an autoimmune disorder that primarily affects the optic nerves and the spinal cord. It can lead to vision loss and paralysis. Treatment involves immunosuppressive medications to manage the immune response.

34. Neuropathy: Neuropathy is a condition characterized by damage to the peripheral nerves, resulting in symptoms such as pain, tingling, and numbness. It can be caused by various factors, including diabetes, infections, and trauma. Managing the underlying cause and using medications for symptom relief are key to neuropathy management.

35. Neurosis: Neurosis refers to a group of mental disorders characterized by excessive anxiety and emotional distress. It can manifest as phobias, obsessive-compulsive behaviors, or generalized anxiety. Psychotherapy and medications may be used to manage neurosis.

36. Neutropenia: Neutropenia is a condition where the body has an abnormally low level of neutrophils, a type of white blood cell that helps fight infections. It can be caused by various factors, including chemotherapy or certain medications. Monitoring blood counts and treating the underlying cause are essential for managing neutropenia.

37. Nicotine Addiction: Nicotine addiction is the dependence on nicotine, a highly addictive substance found in tobacco products. Quitting smoking or using nicotine replacement therapies and counseling can help overcome nicotine addiction.

38. Nicotine Dependence: Nicotine dependence refers to the physical and psychological reliance on nicotine. Breaking the cycle of dependence requires strategies such as behavioral therapy and support.

39. Niemann-Pick Disease: Niemann-Pick disease is a group of inherited metabolic disorders that lead to the accumulation of lipids in cells, affecting various organs. There are different types of Niemann-Pick disease, each with distinct symptoms and treatments.

40. Night Blindness: Night blindness, or nyctalopia, is a condition where individuals have difficulty seeing in low light or at night. It can be caused by vitamin A deficiency or other underlying eye conditions. Addressing the root cause and ensuring a balanced diet are essential for managing night blindness.

41. Nipah Virus Disease: Nipah virus disease is a zoonotic viral infection that can cause severe respiratory and neurological symptoms in humans. It is primarily transmitted from animals to humans and can lead to outbreaks in certain regions. Prevention involves avoiding contact with infected animals and maintaining good hygiene practices.

42. Nocardia Infection: Nocardia infection is a bacterial infection that can affect the lungs, skin, and brain. It is often seen in individuals with weakened immune systems. Treatment involves a course of antibiotics tailored to the specific type of Nocardia.

43. Nocardiosis: Nocardiosis is the disease caused by the Nocardia bacteria. It can manifest as lung infections or affect other parts of the body. Prompt diagnosis and appropriate antibiotic therapy are essential for managing nocardiosis.

44. Nocturia: Nocturia is a condition where individuals wake up frequently during the night to urinate. It can be caused by various factors, including bladder problems and certain medications. Identifying the underlying cause and making lifestyle adjustments can help manage nocturia.

45. Non-alcoholic Fatty Liver Disease (NAFLD): Non-alcoholic fatty liver disease is a condition where excess fat accumulates in the liver, not caused by alcohol consumption. It can progress to more severe conditions like nonalcoholic steatohepatitis (NASH) and liver cirrhosis. Lifestyle changes, such as a healthy diet and exercise, are crucial for managing NAFLD.

46. Nonallergic Rhinitis: Nonallergic rhinitis is a chronic inflammation of the nasal passages that is not caused by allergies. It can be triggered by various factors such as weather changes, strong odors, or certain medications. Symptomatic relief and avoidance of triggers are the mainstays of management.

47. Non-celiac Gluten Sensitivity: Non-celiac gluten sensitivity is a condition where individuals experience symptoms similar to those of celiac disease when consuming gluten, even though they do not have celiac disease or wheat allergy. Adopting a gluten-free diet can help manage non-celiac gluten sensitivity.

48. Non-gonococcal Urethritis (NGU): Non-gonococcal urethritis is inflammation of the urethra not caused by the gonorrhea bacterium. It is often sexually transmitted and requires antibiotic treatment.

49. Non-Hodgkin Lymphoma: Non-Hodgkin lymphoma is a group of cancers that affect the lymphatic system. It can manifest in various ways and requires specific treatment depending on the type and stage of the lymphoma.

50. Nonparalytic Polio: Nonparalytic polio, also known as abortive polio, is a mild form of polio infection that does not lead to paralysis. Most cases resolve on their own, and supportive care is provided to manage symptoms.

51. Non-Small Cell Lung Cancer: Non-small cell lung cancer is the most common type of lung cancer. It includes different subtypes, and treatment options depend on the stage and characteristics of the tumor.

52. Nonvenereal Treponematoses: Nonvenereal treponematoses are a group of infectious diseases caused by Treponema bacteria that are not sexually transmitted. Examples include yaws, bejel, and pinta. These diseases primarily affect the skin, bones, and mucous membranes. Antibiotics are used for treatment, and public health measures aim to control their spread.

53. Noonan Syndrome: Noonan syndrome is a genetic disorder that affects various body systems, leading to characteristic facial features, heart defects, and growth abnormalities. Early diagnosis and management of associated health issues are essential for individuals with Noonan syndrome.

54. Noonan-like Syndrome: Noonan-like syndrome is a group of rare genetic disorders that share some features with Noonan syndrome but may have distinct genetic causes and clinical presentations. Treatment is tailored to address specific symptoms and complications.

55. Norovirus: Norovirus is a highly contagious virus that causes gastroenteritis, leading to symptoms such as vomiting, diarrhea, and abdominal pain. It spreads through contaminated food, water, and surfaces. Hydration is essential for managing norovirus infection.

56. Norovirus Infection: Norovirus infection refers to the illness caused by norovirus. Outbreaks can occur in places with close person-to-person contact, such as schools and cruise ships. Preventive measures include proper hygiene and sanitation practices.

57. Norrie Disease: Norrie disease is a rare genetic disorder that primarily affects the eyes, causing vision loss or blindness. There is no cure, and management focuses on supportive measures and early intervention for associated complications.

58. Nosebleed: Nosebleeds, or epistaxis, are common and often occur due to nasal dryness or minor trauma. Most nosebleeds can be managed by applying pressure and tilting the head forward.

59. Novovirus Infection: Novovirus infection is a viral gastrointestinal illness that can cause symptoms similar to norovirus infection. It is commonly transmitted through contaminated food and water. Hydration and rest are essential for managing novovirus infection.

60. Nut Allergy: A nut allergy is an allergic reaction to nuts, such as peanuts or tree nuts. It can cause severe symptoms and, in some cases, life-threatening anaphylaxis. Avoiding nuts and carrying epinephrine auto-injectors are crucial for individuals with nut allergies.

61. Nutcracker Esophagus: Nutcracker esophagus is a motility disorder of the esophagus characterized by abnormally strong contractions during swallowing. It can cause chest pain and difficulty swallowing. Treatment options may include medications and lifestyle changes.

62. Nutcracker Syndrome: Nutcracker syndrome occurs when the left renal vein is compressed between the aorta and the superior mesenteric artery, leading to blood flow obstruction from the left kidney. Management may involve surgery to alleviate the compression.

63. Nystagmus: Nystagmus is a condition where involuntary, rhythmic eye movements occur. It can affect vision and balance. Nystagmus may be congenital or acquired and requires evaluation by an ophthalmologist or neurologist to determine the underlying cause and appropriate management.


I hope you found this article “Diseases That Start With N” helpful and got insights into some of the rare and lesser-known medical conditions.

Also, keep in mind that, this isn’t an exhaustive list, if there are any Diseases starting with the letter N.

Feel free to leave a comment below with the missing Disease and I’ll update the list as soon as possible.

And, if you’d like to explore more Diseases starting with different letters of the alphabet, click the link below:

  • Diseases That Start With O
  • Diseases That Start With P
  • Diseases That Start With Q
  • Diseases That Start With R

Leave a Comment

Your email address will not be published. Required fields are marked *

Scroll to Top